3RAJ

Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7

Summary for 3RAJ

Entry DOI	10.2210/pdb3raj/pdb
Descriptor	ADP-ribosyl cyclase 1, heavy chain of the Fab fragment of antibody HB7, light chain of the Fab fragment of antibody HB7 (3 entities in total)
Functional Keywords	cd38, adp-ribosyl cyclase, cyclic adp-ribose, x-crystallography, calcium signaling, agonistic antibody, hb7, hydrolase-immune system complex, hydrolase/immune system
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type II membrane protein: P28907
Total number of polymer chains	3
Total formula weight	76693.96
Authors	Zhang, H.,Lee, H.C.,Hao, Q. (deposition date: 2011-03-28, release date: 2011-04-27, Last modification date: 2023-11-01)
Primary citation	Zhang, H.,Zhao, Y.J.,Hao, Q.,Lee, H.C. Engineering a novel cytosolic form of CD38 for cyclic ADP-ribose dependent signaling To be Published,
Experimental method	X-RAY DIFFRACTION (3.044 Å)

Structure validation