3RAJ

Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7

3RAJ の概要

• エントリーDOI: 10.2210/pdb3raj/pdb
• 分子名称: ADP-ribosyl cyclase 1, heavy chain of the Fab fragment of antibody HB7, light chain of the Fab fragment of antibody HB7 (3 entities in total)
• 機能のキーワード: cd38, adp-ribosyl cyclase, cyclic adp-ribose, x-crystallography, calcium signaling, agonistic antibody, hb7, hydrolase-immune system complex, hydrolase/immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type II membrane protein: P28907
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 76693.96

構造登録者

Zhang, H.,Lee, H.C.,Hao, Q. (登録日: 2011-03-28, 公開日: 2011-04-27, 最終更新日: 2023-11-01)

• 主引用文献: Zhang, H.,Zhao, Y.J.,Hao, Q.,Lee, H.C.; Engineering a novel cytosolic form of CD38 for cyclic ADP-ribose dependent signaling; To be Published,

実験手法

X-RAY DIFFRACTION (3.044 Å)