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3R7M

AKR1C3 complex with sulindac

Summary for 3R7M
Entry DOI10.2210/pdb3r7m/pdb
DescriptorAldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid, ... (5 entities in total)
Functional Keywordstim barrel, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P42330
Total number of polymer chains1
Total formula weight39201.32
Authors
Yosaatmadja, Y.,Teague, R.M.,Flanagan, J.U.,Squire, C.J. (deposition date: 2011-03-22, release date: 2012-05-02, Last modification date: 2023-09-13)
Primary citationFlanagan, J.U.,Yosaatmadja, Y.,Teague, R.M.,Chai, M.Z.,Turnbull, A.P.,Squire, C.J.
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.
Plos One, 7:e43965-e43965, 2012
Cited by
PubMed: 22937138
DOI: 10.1371/journal.pone.0043965
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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