3R6R
Structure of the complex of an intramolecular human telomeric DNA with Berberine formed in K+ solution
Summary for 3R6R
| Entry DOI | 10.2210/pdb3r6r/pdb |
| Descriptor | DNA (22-mer), POTASSIUM ION, BERBERINE, ... (4 entities in total) |
| Functional Keywords | dna-drug complex, g-quadruplex, human telomeric dna, dna, dna-antibiotic complex, dna/antibiotic |
| Total number of polymer chains | 1 |
| Total formula weight | 8407.14 |
| Authors | Ferraroni, M.,Bazzicalupi, C.,Gratteri, P.,Bilia, A.R. (deposition date: 2011-03-22, release date: 2012-02-29, Last modification date: 2023-09-13) |
| Primary citation | Bazzicalupi, C.,Ferraroni, M.,Bilia, A.R.,Scheggi, F.,Gratteri, P. The crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1. Nucleic Acids Res., 41:632-638, 2013 Cited by PubMed: 23104378DOI: 10.1093/nar/gks1001 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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