Crystal structure of PPARgammaLBD complexed with the agonist magnolol

Summary for 3R5N

DescriptorPeroxisome proliferator-activated receptor gamma, 5,5'-di(prop-2-en-1-yl)biphenyl-2,2'-diol (3 entities in total)
Functional Keywordsnuclear receptor, transcription factor, transcription-transcription agonist complex, transcription/transcription agonist
Biological sourceHomo sapiens (human)
Cellular locationNucleus P37231
Total number of polymer chains1
Total molecular weight31854.06
Zhang, H.,Chen, L.,Chen, J.,Hu, L.,Jiang, H.,Shen, X. (deposition date: 2011-03-18, release date: 2012-02-08)
Primary citation
Zhang, H.,Xu, X.,Chen, L.,Chen, J.,Hu, L.,Jiang, H.,Shen, X.
Molecular determinants of magnolol targeting both RXR(alpha) and PPAR(gamma).
Plos One, 6:e28253-e28253, 2011
PubMed: 22140563 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pone.0028253
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.277305.7%5.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report