3R2J

Crystal Structure of PnC1 from L. infantum in complex with nicotinate

Summary for 3R2J

Entry DOI	10.2210/pdb3r2j/pdb
Descriptor	Alpha/beta-hydrolase-like protein, ZINC ION, NICOTINIC ACID, ... (5 entities in total)
Functional Keywords	alpha/beta-hydrolase-like, nicotinamidase, cytoplasmic, hydrolase
Biological source	Leishmania infantum
Total number of polymer chains	4
Total formula weight	97012.30
Authors	Gazanion, E.,Garcia, D.,Guichou, J.-F.,Labesse, G.,Sereno, D.,Vergnes, B. (deposition date: 2011-03-14, release date: 2011-08-24, Last modification date: 2023-09-13)
Primary citation	Gazanion, E.,Garcia, D.,Silvestre, R.,Gerard, C.,Guichou, J.F.,Labesse, G.,Seveno, M.,Cordeiro-Da-Silva, A.,Ouaissi, A.,Sereno, D.,Vergnes, B. The Leishmania nicotinamidase is essential for NAD(+) production and parasite proliferation. Mol.Microbiol., 82:21-38, 2011 Cited by PubMed: 21819459 DOI: 10.1111/j.1365-2958.2011.07799.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.68 Å)

Structure validation