3R18

Chicken sulfite oxidase double mutant with altered activity and substrate affinity

Summary for 3R18

Entry DOI	10.2210/pdb3r18/pdb
Related	1SOX 2A99 2BII 3HBG
Descriptor	Sulfite oxidase, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, MOLYBDENUM ATOM, ... (4 entities in total)
Functional Keywords	molybdenum, molybdopterin, sulfite oxidase, nitrate reductase, oxotransferase, metal binding, nitrogen assimilation, oxidoreductase
Biological source	Gallus gallus (bantam,chickens)
Cellular location	Mitochondrion intermembrane space: P07850
Total number of polymer chains	1
Total formula weight	51417.41
Authors	Qiu, J.A.,Wilson, H.L.,Rajagopalan, K.V. (deposition date: 2011-03-09, release date: 2012-02-08, Last modification date: 2023-09-13)
Primary citation	Qiu, J.A.,Wilson, H.L.,Rajagopalan, K.V. Structure-based alteration of substrate specificity and catalytic activity of sulfite oxidase from sulfite oxidation to nitrate reduction. Biochemistry, 51:1134-1147, 2012 Cited by PubMed: 22263579 DOI: 10.1021/bi201206v PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation