3QYZ

Crystal structure of ERK2 in complex with an inhibitor

3QYZ の概要

• エントリーDOI: 10.2210/pdb3qyz/pdb
• 関連するPDBエントリー: 3QYU 3QYW
• 分子名称: Mitogen-activated protein kinase 1, 5'-azido-8-bromo-5'-deoxyadenosine, DIMETHYL SULFOXIDE, ... (6 entities in total)
• 機能のキーワード: transferase, serine/threonine-protein kinase, atp-binding cell cycle, phosphorylation, protein kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Rattus norvegicus (brown rat,rat,rats)
• 細胞内の位置: Cytoplasm, cytoskeleton, spindle : P63086
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43736.42

構造登録者

Gelin, M.,Pochet, S.,Hoh, F.,Pirochi, M.,Guichou, J.-F.,Ferrer, J.-L.,Labesse, G. (登録日: 2011-03-04, 公開日: 2011-08-24, 最終更新日: 2017-11-08)

• 主引用文献: le Maire, A.,Gelin, M.,Pochet, S.,Hoh, F.,Pirocchi, M.,Guichou, J.F.,Ferrer, J.L.,Labesse, G.; In-plate protein crystallization, in situ ligand soaking and X-ray diffraction.; Acta Crystallogr.,Sect.D, 67:747-755, 2011; PubMed: 21904027; DOI: 10.1107/S0907444911023249

実験手法

X-RAY DIFFRACTION (1.46 Å)