3QYX

Crystal structure of Mycobacterium tuberculosis EspR in complex with a small DNA fragment

Summary for 3QYX

• Entry DOI: 10.2210/pdb3qyx/pdb
• Related: 3QF3 3QWG
• Descriptor: ESX-1 secretion-associated regulator EspR, 5'-D(*A*CP*GP*CP*CP*GP*AP*AP*TP*C)-3' (2 entities in total)
• Functional Keywords: n-terminal hth motif, c-terminal dimerization domain, dna-binding, transcription factor, dimer of dimers binding dna, transcription activator, transcription-dna complex, transcription/dna
• Biological source: Mycobacterium tuberculosis
• Cellular location: Secreted: P96228
• Total number of polymer chains: 5
• Total formula weight: 61980.38

Authors

Blasco, B.,Pojer, F.,Cole, S.T. (deposition date: 2011-03-04, release date: 2011-09-14, Last modification date: 2024-04-03)

• Primary citation: Blasco, B.,Stenta, M.,Alonso-Sarduy, L.,Dietler, G.,Peraro, M.D.,Cole, S.T.,Pojer, F.; Atypical DNA recognition mechanism used by the EspR virulence regulator of Mycobacterium tuberculosis.; Mol.Microbiol., 82:251-264, 2011; PubMed: 21883526; DOI: 10.1111/j.1365-2958.2011.07813.x

Experimental method

X-RAY DIFFRACTION (3.75 Å)