3QUD

Human p38 MAP Kinase in Complex with 2-amino-phenylamino-benzophenone

Summary for 3QUD

• Entry DOI: 10.2210/pdb3qud/pdb
• Related: 3QUE
• Descriptor: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside, {4-[(2-aminophenyl)amino]phenyl}(phenyl)methanone, ... (4 entities in total)
• Functional Keywords: kinase domain, phosphate transferase, benzophenone derivative, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 42142.14

Authors

Gruetter, C.,Rauh, D. (deposition date: 2011-02-23, release date: 2012-04-11, Last modification date: 2023-11-01)

• Primary citation: Karcher, S.C.,Fischer, S.,Schattel, V.,Romir, J.,Stehle, T.,Gruetter, C.,Rauh, D.,Laufer, S.A.; Resolving the selectivity problem for p38 mitogen activated protein (MAP) Kinase-inhibitors: Development of new highly potent inhibitors of p38 MAP kinase with an outstanding selectivity profile; To be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)