3QTC
Crystal structure of the catalytic domain of MmOmeRS, an O-methyl tyrosyl-tRNA synthetase evolved from Methanosarcina mazei PylRS, complexed with O-methyl tyrosine and AMP-PNP
Summary for 3QTC
Entry DOI | 10.2210/pdb3qtc/pdb |
Descriptor | Pyrrolysyl-tRNA synthetase, MAGNESIUM ION, O-methyl-L-tyrosine, ... (6 entities in total) |
Functional Keywords | pyrrolysyl-trna synthetase, aminoacyl-trna synthetase, atp binding, o-methyl tyrosine binding, magnesium binding, aminoacylation, esterification, ligase |
Biological source | Methanosarcina mazei (Methanosarcina frisia) |
Cellular location | Cytoplasm (By similarity): Q8PWY1 |
Total number of polymer chains | 1 |
Total formula weight | 34555.75 |
Authors | Dellas, N.,Takimoto, J.K.,Noel, J.P.,Wang, L. (deposition date: 2011-02-22, release date: 2011-05-25, Last modification date: 2023-12-06) |
Primary citation | Takimoto, J.K.,Dellas, N.,Noel, J.P.,Wang, L. Stereochemical Basis for Engineered Pyrrolysyl-tRNA Synthetase and the Efficient in Vivo Incorporation of Structurally Divergent Non-native Amino Acids. Acs Chem.Biol., 6:733-743, 2011 Cited by PubMed: 21545173DOI: 10.1021/cb200057a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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