Revealing a steroid receptor ligand as a unique PPARgamma agonist

Summary for 3QT0

DescriptorPeroxisome proliferator-activated receptor gamma, Nuclear receptor coactivator 1 peptide, 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE, ... (4 entities in total)
Functional Keywordsppar gamma lbd domain, transcription
Biological sourceHomo sapiens (human)
Cellular locationNucleus P37231
Nucleus (By similarity) Q15788
Total number of polymer chains2
Total molecular weight33331.8
Rong, H. (deposition date: 2011-02-22, release date: 2012-02-29, Last modification date: 2013-08-28)
Primary citation
Lin, S.,Han, Y.,Shi, Y.,Rong, H.,Zheng, S.,Jin, S.,Lin, S.Y.,Lin, S.C.,Li, Y.
Revealing a steroid receptor ligand as a unique PPAR gamma agonist.
Cell Res., 22:746-756, 2012
PubMed: 21986665 (PDB entries with the same primary citation)
DOI: 10.1038/cr.2011.162
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.281271.8%14.4%6.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report