3QPZ

Crystal structure of the N59A mutant of the 3-deoxy-d-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis

3QPZ の概要

• エントリーDOI: 10.2210/pdb3qpz/pdb
• 関連するPDBエントリー: 3QPY 3QQ0 3QQ1
• 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, PHOSPHATE ION, ... (6 entities in total)
• 機能のキーワード: manno-octulosonate, synthase, lipopolysaccharide, kdop, kdo8p, kdops, kdo8ps, tim barrel, transferase
• 由来する生物種: Neisseria meningitidis
• 細胞内の位置: Cytoplasm (By similarity): Q9JZ55
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 122490.99

構造登録者

Allison, T.M.,Jameson, G.B.,Parker, E.J.,Cochrane, F.C. (登録日: 2011-02-14, 公開日: 2011-04-13, 最終更新日: 2023-11-01)

• 主引用文献: Allison, T.M.,Hutton, R.D.,Cochrane, F.C.,Yeoman, J.A.,Jameson, G.B.,Parker, E.J.; Targeting the role of a key conserved motif for substrate selection and catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase; Biochemistry, 50:3686-3695, 2011; PubMed: 21438567; DOI: 10.1021/bi200251f

実験手法

X-RAY DIFFRACTION (1.75 Å)