3QPZ
Crystal structure of the N59A mutant of the 3-deoxy-d-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 281 |
| Chain | Residue |
| A | LYS52 |
| A | GLN110 |
| A | LYS135 |
| A | HIS199 |
| A | PHE234 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 282 |
| Chain | Residue |
| A | ALA113 |
| A | PHE114 |
| A | GLN138 |
| A | ARG165 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 281 |
| Chain | Residue |
| B | ALA103 |
| B | GLU104 |
| B | VAL105 |
| B | CYS106 |
| B | ASP107 |
| B | HOH389 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 282 |
| Chain | Residue |
| B | LYS52 |
| B | GLN110 |
| B | LYS135 |
| B | PHE234 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 283 |
| Chain | Residue |
| B | PRO137 |
| B | GLN138 |
| B | ARG165 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL C 281 |
| Chain | Residue |
| C | ARG229 |
| C | ILE276 |
| C | LEU277 |
| C | HOH342 |
| C | HOH344 |
| C | HOH525 |
| D | LEU219 |
| D | ARG263 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 282 |
| Chain | Residue |
| C | GLN110 |
| C | LYS135 |
| C | HIS199 |
| C | PHE234 |
| C | HOH414 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 283 |
| Chain | Residue |
| C | ALA113 |
| C | GLN138 |
| C | ARG165 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA C 284 |
| Chain | Residue |
| C | ALA103 |
| C | CYS106 |
| C | ASN130 |
| C | HOH333 |
| C | HOH369 |
| C | HOH622 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL D 281 |
| Chain | Residue |
| D | LYS82 |
| D | ALA103 |
| D | GLU104 |
| D | VAL105 |
| D | ASP107 |
| D | ASN130 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 282 |
| Chain | Residue |
| D | GLN110 |
| D | LYS135 |
| D | HIS199 |
| D | PHE234 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 283 |
| Chain | Residue |
| D | ALA113 |
| D | GLN138 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01406","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
