3QOW
DOT1L Structure in complex with SAM
Summary for 3QOW
Entry DOI | 10.2210/pdb3qow/pdb |
Related | 3QOX |
Descriptor | Histone-lysine N-methyltransferase, S-ADENOSYLMETHIONINE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | h3k79 methylation, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (Probable): Q8TEK3 |
Total number of polymer chains | 1 |
Total formula weight | 49287.99 |
Authors | |
Primary citation | Richon, V.M.,Johnston, D.,Sneeringer, C.J.,Jin, L.,Majer, C.R.,Elliston, K.,Jerva, L.F.,Scott, M.P.,Copeland, R.A. Chemogenetic analysis of human protein methyltransferases. Chem.Biol.Drug Des., 78:199-210, 2011 Cited by PubMed: 21564555DOI: 10.1111/j.1747-0285.2011.01135.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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