3QMC
Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1
Summary for 3QMC
Entry DOI | 10.2210/pdb3qmc/pdb |
Related | 3QMB 3QMD 3QMG 3QMH 3QMI |
Descriptor | CpG-binding protein, 5'-D(*GP*CP*CP*AP*CP*CP*GP*CP*TP*GP*GP*C)-3', 5'-D(*GP*CP*CP*AP*GP*CP*GP*GP*TP*GP*GP*C)-3', ... (5 entities in total) |
Functional Keywords | structural genomics consortium, sgc, cxxc-type zn finger, dna binding, unmethylated cpg motifs, nucleus speckle, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus speckle : Q9P0U4 |
Total number of polymer chains | 3 |
Total formula weight | 16987.54 |
Authors | Lam, R.,Xu, C.,Bian, C.B.,Kania, J.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2011-02-04, release date: 2011-02-23, Last modification date: 2023-09-13) |
Primary citation | Xu, C.,Bian, C.,Lam, R.,Dong, A.,Min, J. The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. Nat Commun, 2:227-227, 2011 Cited by PubMed: 21407193DOI: 10.1038/ncomms1237 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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