3QLP

X-ray structure of the complex between human alpha thrombin and a modified thrombin binding aptamer (mTBA)

3QLP の概要

• エントリーDOI: 10.2210/pdb3qlp/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000020
• 分子名称: Thrombin heavy chain, Thrombin light chain, modified thrombin binding DNA aptamer, ... (8 entities in total)
• 機能のキーワード: protein-dna complex, serine protease, blood coagulation, aptamer, serine protease fold, hydrolase-hydrolase inhibitor-dna complex, hydrolase/hydrolase inhibitor/dna
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 39357.09

構造登録者

Russo Krauss, I.,Merlino, A.,Mazzarella, L.,Sica, F. (登録日: 2011-02-03, 公開日: 2011-10-19, 最終更新日: 2020-07-29)

• 主引用文献: Russo Krauss, I.,Merlino, A.,Giancola, C.,Randazzo, A.,Mazzarella, L.,Sica, F.; Thrombin-aptamer recognition: a revealed ambiguity.; Nucleic Acids Res., 39:7858-7867, 2011; PubMed: 21715374; DOI: 10.1093/nar/gkr522

実験手法

X-RAY DIFFRACTION (2.14 Å)