3QKV

Crystal structure of fatty acid amide hydrolase with small molecule compound

Summary for 3QKV

Entry DOI	10.2210/pdb3qkv/pdb
Related	3QJ8 3QJ9 3QK5
Descriptor	Fatty-acid amide hydrolase 1, (6-bromo-1'H,4H-spiro[1,3-benzodioxine-2,4'-piperidin]-1'-yl)methanol (2 entities in total)
Functional Keywords	protein-inhibitor complex, faah, fatty-acid amide hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Rattus norvegicus (rat)
Cellular location	Endoplasmic reticulum membrane; Single-pass membrane protein: P97612
Total number of polymer chains	2
Total formula weight	129814.71
Authors	Min, X.,Walker, N.P.C.,Wang, Z. (deposition date: 2011-02-01, release date: 2011-04-27, Last modification date: 2023-09-13)
Primary citation	Min, X.,Thibault, S.T.,Porter, A.C.,Gustin, D.J.,Carlson, T.J.,Xu, H.,Lindstrom, M.,Xu, G.,Uyeda, C.,Ma, Z.,Li, Y.,Kayser, F.,Walker, N.P.,Wang, Z. Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH). Proc.Natl.Acad.Sci.USA, 108:7379-7384, 2011 Cited by PubMed: 21502526 DOI: 10.1073/pnas.1016167108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation