3QKJ

The PWWP domain of human DNA (CYTOSINE-5-)-METHYLTRANSFERASE 3 BETA in complex with a bis-tris molecule

3QKJ の概要

• エントリーDOI: 10.2210/pdb3qkj/pdb
• 分子名称: DNA cytosine-5 methyltransferase 3 beta isoform 6 variant, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: dnmt3b, pwwp domain, methyltransferase 3 beta, sgc, s-adenosyl-l-methionine, transferase, zinc-finger, structural genomics, structural genomics consortium
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 68436.92

構造登録者

Zeng, H.,Amaya, M.F.,Mackenzie, F.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Botchkarev, A.,Min, J.,Wu, H.,Structural Genomics Consortium (SGC) (登録日: 2011-02-01, 公開日: 2011-03-09, 最終更新日: 2024-02-21)

• 主引用文献: Wu, H.,Zeng, H.,Lam, R.,Tempel, W.,Amaya, M.F.,Xu, C.,Dombrovski, L.,Qiu, W.,Wang, Y.,Min, J.; Structural and Histone Binding Ability Characterizations of Human PWWP Domains.; Plos One, 6:e18919-e18919, 2011; PubMed: 21720545; DOI: 10.1371/journal.pone.0018919

実験手法

X-RAY DIFFRACTION (2.04 Å)