3QJ5

S-nitrosoglutathione reductase (GSNOR) in complex with N6022

Summary for 3QJ5

• Entry DOI: 10.2210/pdb3qj5/pdb
• Descriptor: Alcohol dehydrogenase class-3, ZINC ION, POTASSIUM ION, ... (9 entities in total)
• Functional Keywords: s-nitrosoglutathione reductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P11766
• Total number of polymer chains: 2
• Total formula weight: 83095.25

Authors

Chun, L.,Kim, H.,Sun, X. (deposition date: 2011-01-28, release date: 2011-04-06, Last modification date: 2024-04-03)

• Primary citation: Sun, X.,Wasley, J.W.,Qiu, J.,Blonder, J.P.,Stout, A.M.,Green, L.S.,Strong, S.A.,Colagiovanni, D.B.,Richards, J.P.,Mutka, S.C.,Chun, L.,Rosenthal, G.J.; Discovery of s-nitrosoglutathione reductase inhibitors: potential agents for the treatment of asthma and other inflammatory diseases.; ACS Med Chem Lett, 2:402-406, 2011; PubMed: 24900320; DOI: 10.1021/ml200045s

Experimental method

X-RAY DIFFRACTION (1.9 Å)