3QIS

Recognition of the F&H motif by the Lowe Syndrome protein OCRL

Summary for 3QIS

Entry DOI	10.2210/pdb3qis/pdb
Descriptor	Inositol polyphosphate 5-phosphatase OCRL-1, Protein FAM109A (3 entities in total)
Functional Keywords	dent disease, rac1, rab gtpases, appl1, ses2, endocytic pathway, golgi complex, hydrolase-protein binding complex, hydrolase/protein binding
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasmic vesicle, phagosome membrane : Q01968 Early endosome: Q8N4B1
Total number of polymer chains	2
Total formula weight	44243.66
Authors	Pirruccello, M.,Swan, L.E.,Folta-Stogniew, E.,De Camilli, P. (deposition date: 2011-01-27, release date: 2011-06-15, Last modification date: 2023-09-13)
Primary citation	Pirruccello, M.,Swan, L.E.,Folta-Stogniew, E.,De Camilli, P. Recognition of the F&H motif by the Lowe syndrome protein OCRL. Nat.Struct.Mol.Biol., 18:789-795, 2011 Cited by PubMed: 21666675 DOI: 10.1038/nsmb.2071 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation