3QHY
Structural, thermodynamic and kinetic analysis of the picomolar binding affinity interaction of the beta-lactamase inhibitor protein-II (BLIP-II) with class A beta-lactamases
Summary for 3QHY
Entry DOI | 10.2210/pdb3qhy/pdb |
Related | 1JTD 1JTG 3QI0 |
Descriptor | Beta-lactamase, Beta-lactamase inhibitory protein II (3 entities in total) |
Functional Keywords | enyzme-inhibitor complex, beta-propeller, beta-lactamase, protein:protein interaction, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bacillus anthracis (anthrax,anthrax bacterium) More |
Total number of polymer chains | 2 |
Total formula weight | 58120.56 |
Authors | Brown, N.G.,Chow, D.C.,Sankaran, B.,Zwart, P.,Prasad, B.V.V.,Palzkill, T.,Berkeley Structural Genomics Center (BSGC) (deposition date: 2011-01-26, release date: 2011-07-20, Last modification date: 2023-09-13) |
Primary citation | Brown, N.G.,Chow, D.C.,Sankaran, B.,Zwart, P.,Prasad, B.V.,Palzkill, T. Analysis of the binding forces driving the tight interactions between beta-lactamase inhibitory protein-II (BLIP-II) and class A beta-lactamases. J.Biol.Chem., 286:32723-32735, 2011 Cited by PubMed: 21775426DOI: 10.1074/jbc.M111.265058 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.06 Å) |
Structure validation
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