3QHY

Structural, thermodynamic and kinetic analysis of the picomolar binding affinity interaction of the beta-lactamase inhibitor protein-II (BLIP-II) with class A beta-lactamases

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Beta-lactamase	polymer	271	29759.6	1	UniProt (Q93T42) Pfam (PF00144) Pfam (PF13354)	Bacillus anthracis (anthrax anthrax bacterium)	Beta-lactamase Bla1, Beta-lactamase I
2	B (B)	Beta-lactamase inhibitory protein II	polymer	282	28360.9	1	UniProt (O87916) Pfam (PF13540)	Streptomyces exfoliatus (Streptomyces hydrogenans)
3	C, D (A, B)	water	water		18.0	508	Chemie (HOH)

Sequence modifications

B: 41 - 311 (UniProt: O87916)

PDB	External Database	Details
Gly 312	-	expression tag
Ser 313	-	expression tag
Gly 314	-	expression tag
Ser 315	-	expression tag
Gly 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag
His 319	-	expression tag
His 320	-	expression tag
His 321	-	expression tag
His 322	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58120.6
All*	Total formula weight	58120.6

*Water molecules are not included.