3QHY

Structural, thermodynamic and kinetic analysis of the picomolar binding affinity interaction of the beta-lactamase inhibitor protein-II (BLIP-II) with class A beta-lactamases

3QHY の概要

• エントリーDOI: 10.2210/pdb3qhy/pdb
• 関連するPDBエントリー: 1JTD 1JTG 3QI0
• 分子名称: Beta-lactamase, Beta-lactamase inhibitory protein II (3 entities in total)
• 機能のキーワード: enyzme-inhibitor complex, beta-propeller, beta-lactamase, protein:protein interaction, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Bacillus anthracis (anthrax,anthrax bacterium); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 58120.56

構造登録者

Brown, N.G.,Chow, D.C.,Sankaran, B.,Zwart, P.,Prasad, B.V.V.,Palzkill, T.,Berkeley Structural Genomics Center (BSGC) (登録日: 2011-01-26, 公開日: 2011-07-20, 最終更新日: 2023-09-13)

• 主引用文献: Brown, N.G.,Chow, D.C.,Sankaran, B.,Zwart, P.,Prasad, B.V.,Palzkill, T.; Analysis of the binding forces driving the tight interactions between beta-lactamase inhibitory protein-II (BLIP-II) and class A beta-lactamases.; J.Biol.Chem., 286:32723-32735, 2011; PubMed: 21775426; DOI: 10.1074/jbc.M111.265058

実験手法

X-RAY DIFFRACTION (2.06 Å)