3QD5

Crystal structure of a putative ribose-5-phosphate isomerase from Coccidioides immitis solved by combined iodide ion SAD and MR

Summary for 3QD5

• Entry DOI: 10.2210/pdb3qd5/pdb
• Descriptor: putative ribose-5-phosphate isomerase, 1,2-ETHANEDIOL, IODIDE ION, ... (4 entities in total)
• Functional Keywords: structural genomics, seattle structural genomics center for infectious disease, ssgcid, coccidioidomycosis, putative uncharacterized protein, hypothetical protein, ribose-5-phosphate isomerase, iodide ion, isomerase
• Biological source: Coccidioides immitis
• Total number of polymer chains: 2
• Total formula weight: 39272.91

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2011-01-17, release date: 2011-02-09, Last modification date: 2024-11-27)

Primary citation

Edwards, T.E.,Abramov, A.B.,Smith, E.R.,Baydo, R.O.,Leonard, J.T.,Leibly, D.J.,Thompkins, K.B.,Clifton, M.C.,Gardberg, A.S.,Staker, B.L.,Van Voorhis, W.C.,Myler, P.J.,Stewart, L.J.
Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis.
Bmc Struct.Biol., 11:39-39, 2011

PubMed Abstract: Ribose-5-phosphate isomerase is an enzyme that catalyzes the interconversion of ribose-5-phosphate and ribulose-5-phosphate. This family of enzymes naturally occurs in two distinct classes, RpiA and RpiB, which play an important role in the pentose phosphate pathway and nucleotide and co-factor biogenesis.

PubMed: 21995815
DOI: 10.1186/1472-6807-11-39

Experimental method

X-RAY DIFFRACTION (1.9 Å)