3QBQ

Crystal structure of extracellular domains of mouse RANK-RANKL complex

「3NZY」から置き換えられました

3QBQ の概要

• エントリーDOI: 10.2210/pdb3qbq/pdb
• 分子名称: Tumor necrosis factor ligand superfamily member 11, Tumor necrosis factor receptor superfamily member 11A (3 entities in total)
• 機能のキーワード: tumor necrosis factor (tnf) ligand-receptor superfamily fold, cytokine-cytokine receptor complex, cytokine/cytokine receptor
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Isoform 1: Cell membrane; Single-pass type II membrane protein. Isoform 2: Cell membrane; Single-pass type II membrane protein. Isoform 3: Cytoplasm. Tumor necrosis factor ligand superfamily member 11, soluble form: Secreted: O35235; Membrane; Single-pass type I membrane protein (Potential): O35305
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 73058.15

構造登録者

Ta, H.M.,Nguyen, G.T.T.,Jin, H.M.,Choi, J.K.,Park, H.,Kim, N.S.,Hwang, H.Y.,Kim, K.K. (登録日: 2011-01-13, 公開日: 2011-03-02, 最終更新日: 2023-11-01)

• 主引用文献: Ta, H.M.,Nguyen, G.T.T.,Jin, H.M.,Choi, J.K.,Park, H.,Kim, N.S.,Hwang, H.Y.,Kim, K.K.; Structure-based development of a receptor activator of nuclear factor-kappaB ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosis; Proc.Natl.Acad.Sci.USA, 107:20281-20286, 2010; PubMed: 21059944; DOI: 10.1073/pnas.1011686107

実験手法

X-RAY DIFFRACTION (2.5 Å)