3Q9I

LVFFA segment from Alzheimer's Amyloid-Beta displayed on 42-membered macrocycle scaffold, bromide derivative

Summary for 3Q9I

• Entry DOI: 10.2210/pdb3q9i/pdb
• Related: 3Q9G 3Q9H 3Q9J
• Descriptor: Cyclic pseudo-peptide LV(4BF)FA(ORN)(HAO)LK(ORN), CHLORIDE ION, GLYCEROL, ... (5 entities in total)
• Functional Keywords: beta sheet tetramer, beta strand, protein fibril
• Total number of polymer chains: 8
• Total formula weight: 11688.24

Authors

Liu, C.,Sawaya, M.R.,Eisenberg, D.,Nowick, J.S.,Cheng, P.,Zheng, J. (deposition date: 2011-01-07, release date: 2011-06-08, Last modification date: 2023-11-15)

• Primary citation: Liu, C.,Sawaya, M.R.,Cheng, P.N.,Zheng, J.,Nowick, J.S.,Eisenberg, D.; Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics.; J.Am.Chem.Soc., 133:6736-6744, 2011; PubMed: 21473620; DOI: 10.1021/ja200222n

Experimental method

X-RAY DIFFRACTION (1.99 Å)