3Q7U

Structure of Mtb 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD) complexed with CTP

Summary for 3Q7U

• Entry DOI: 10.2210/pdb3q7u/pdb
• Related: 3OKR 3Q80
• Descriptor: 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase, MAGNESIUM ION, CYTIDINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: tb structural genomics consortium, tbsgc, rossmann fold, 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase, transferase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 2
• Total formula weight: 49141.67

Authors

Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Ioerger, T.R.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2011-01-05, release date: 2011-05-04, Last modification date: 2023-09-13)

• Primary citation: Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Ioerger, T.R.,Sacchettini, J.C.; Crystal Structure of Mycobacterium tuberculosis 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD): a candidate antitubercular drug target; Proteins, 2011

Experimental method

X-RAY DIFFRACTION (2.1 Å)