3Q7G
Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1 in complex with SOS (sucrose octasulfate)
Summary for 3Q7G
Entry DOI | 10.2210/pdb3q7g/pdb |
Related | 3Q7L |
Related PRD ID | PRD_900013 |
Descriptor | Amyloid-like protein 1, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose (3 entities in total) |
Functional Keywords | amyloid beta precursor protein, e2 domain, alzheimer's disease, signaling, heparin, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type I membrane protein. C30: Cytoplasm: P51693 |
Total number of polymer chains | 2 |
Total formula weight | 52624.43 |
Authors | |
Primary citation | Xue, Y.,Lee, S.,Wang, Y.,Ha, Y. Crystal Structure of the E2 Domain of Amyloid Precursor Protein-like Protein 1 in Complex with Sucrose Octasulfate. J.Biol.Chem., 286:29748-29757, 2011 Cited by PubMed: 21715329DOI: 10.1074/jbc.M111.219659 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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