3Q7G

Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1 in complex with SOS (sucrose octasulfate)

Summary for 3Q7G

• Entry DOI: 10.2210/pdb3q7g/pdb
• Related: 3Q7L
• Related PRD ID: PRD_900013
• Descriptor: Amyloid-like protein 1, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose (3 entities in total)
• Functional Keywords: amyloid beta precursor protein, e2 domain, alzheimer's disease, signaling, heparin, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Single-pass type I membrane protein. C30: Cytoplasm: P51693
• Total number of polymer chains: 2
• Total formula weight: 52624.43

Authors

Xue, Y.,Ha, Y. (deposition date: 2011-01-04, release date: 2011-06-22, Last modification date: 2024-02-21)

• Primary citation: Xue, Y.,Lee, S.,Wang, Y.,Ha, Y.; Crystal Structure of the E2 Domain of Amyloid Precursor Protein-like Protein 1 in Complex with Sucrose Octasulfate.; J.Biol.Chem., 286:29748-29757, 2011; PubMed: 21715329; DOI: 10.1074/jbc.M111.219659

Experimental method

X-RAY DIFFRACTION (2.3 Å)