3Q6F
Crystal structure of Fab of human mAb 2909 specific for quaternary neutralizing epitope of HIV-1 gp120
Summary for 3Q6F
Entry DOI | 10.2210/pdb3q6f/pdb |
Related | 3Q6G |
Descriptor | Light chain of Fab of human mAb 2909, Heavy chain of Fab of human mAb 2909, DI(HYDROXYETHYL)ETHER (3 entities in total) |
Functional Keywords | igg, neutralization of hiv-1 viruses, quaternary epitope of hiv-1 gp120, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 288895.88 |
Authors | Spurrier, B.,Sampson, J.,Totrov, M.,Li, H.,O'Neal, T.,William, C.,Robinson, J.,Gorny, M.K.,Zolla-Pazner, S.,Kong, X.P. (deposition date: 2010-12-31, release date: 2011-05-25, Last modification date: 2011-10-12) |
Primary citation | Spurrier, B.,Sampson, J.M.,Totrov, M.,Li, H.,O'Neal, T.,Williams, C.,Robinson, J.,Gorny, M.K.,Zolla-Pazner, S.,Kong, X.P. Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120. Structure, 19:691-699, 2011 Cited by PubMed: 21565703DOI: 10.1016/j.str.2011.02.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.192 Å) |
Structure validation
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