3Q03
Crystal structure of plasminogen activator inhibitor-1 in a metastable active conformation.
Summary for 3Q03
Entry DOI | 10.2210/pdb3q03/pdb |
Related | 1B3K 1DB2 1DVM |
Descriptor | Plasminogen activator inhibitor 1, ZINC ION, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | pai-1, active serpin, serine protease inhibitor, metastable conformation, hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P05121 |
Total number of polymer chains | 2 |
Total formula weight | 85761.79 |
Authors | Jensen, J.K.,Morth, J.P. (deposition date: 2010-12-15, release date: 2011-06-22, Last modification date: 2023-09-13) |
Primary citation | Jensen, J.K.,Thompson, L.C.,Bucci, J.C.,Nissen, P.,Gettins, P.G.,Peterson, C.B.,Andreasen, P.A.,Morth, J.P. Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability. J.Biol.Chem., 286:29709-29717, 2011 Cited by PubMed: 21697084DOI: 10.1074/jbc.M111.236554 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6401 Å) |
Structure validation
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