3PXM

Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and disruption of a distant poly-(L-proline) II helix

Summary for 3PXM

Entry DOI	10.2210/pdb3pxm/pdb
Descriptor	Monellin chain B/Monellin chain A chimeric protein (2 entities in total)
Functional Keywords	a poly-(l-proline) ii (ppii) helix, sweet protein, plant protein
Biological source	Dioscoreophyllum cumminsii (Serendipity berry) More
Total number of polymer chains	2
Total formula weight	22781.99
Authors	Hobbs, J.R.,Templeton, C.M.,Pour, S.O.,Blanch, E.W.,Munger, S.M.,Conn, G.L. (deposition date: 2010-12-10, release date: 2011-04-06, Last modification date: 2023-09-13)
Primary citation	Templeton, C.M.,Ostovar Pour, S.,Hobbs, J.R.,Blanch, E.W.,Munger, S.D.,Conn, G.L. Reduced Sweetness of a Monellin (MNEI) Mutant Results from Increased Protein Flexibility and Disruption of a Distant Poly-(L-Proline) II Helix. Chem Senses, 36:425-434, 2011 Cited by PubMed: 21343241 DOI: 10.1093/chemse/bjr007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation