3PXM

Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and disruption of a distant poly-(L-proline) II helix

3PXM の概要

• エントリーDOI: 10.2210/pdb3pxm/pdb
• 分子名称: Monellin chain B/Monellin chain A chimeric protein (2 entities in total)
• 機能のキーワード: a poly-(l-proline) ii (ppii) helix, sweet protein, plant protein
• 由来する生物種: Dioscoreophyllum cumminsii (Serendipity berry); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22781.99

構造登録者

Hobbs, J.R.,Templeton, C.M.,Pour, S.O.,Blanch, E.W.,Munger, S.M.,Conn, G.L. (登録日: 2010-12-10, 公開日: 2011-04-06, 最終更新日: 2023-09-13)

• 主引用文献: Templeton, C.M.,Ostovar Pour, S.,Hobbs, J.R.,Blanch, E.W.,Munger, S.D.,Conn, G.L.; Reduced Sweetness of a Monellin (MNEI) Mutant Results from Increased Protein Flexibility and Disruption of a Distant Poly-(L-Proline) II Helix.; Chem Senses, 36:425-434, 2011; PubMed: 21343241; DOI: 10.1093/chemse/bjr007

実験手法

X-RAY DIFFRACTION (1.8 Å)