3PX6
Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and ddCTP-dA Mismatch (tautomer) in Closed Conformation
Summary for 3PX6
Entry DOI | 10.2210/pdb3px6/pdb |
Related | 3PV8 3PX0 3PX4 |
Descriptor | DNA polymerase I, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*C*AP*TP*AP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... (7 entities in total) |
Functional Keywords | dna polymerase i, protein-dna complex, transferase-dna complex, cytosine-adenine, closed conformation, transferase/dna |
Biological source | Geobacillus kaustophilus |
Total number of polymer chains | 6 |
Total formula weight | 150180.98 |
Authors | Wang, W.,Beese, L.S. (deposition date: 2010-12-09, release date: 2011-10-19, Last modification date: 2023-09-13) |
Primary citation | Wang, W.,Hellinga, H.W.,Beese, L.S. Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis. Proc.Natl.Acad.Sci.USA, 108:17644-17648, 2011 Cited by PubMed: 22006298DOI: 10.1073/pnas.1114496108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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