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3PWD

Crystal structure of maize CK2 in complex with NBC (Z1)

Summary for 3PWD
Entry DOI10.2210/pdb3pwd/pdb
DescriptorCasein kinase II subunit alpha, 8-hydroxy-4-methyl-9-nitro-2H-benzo[g]chromen-2-one (3 entities in total)
Functional Keywordsprotein kinase, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceZea mays (maize)
Total number of polymer chains1
Total formula weight39562.39
Authors
Battistutta, R.,Mazzorana, M. (deposition date: 2010-12-08, release date: 2011-11-02, Last modification date: 2017-11-08)
Primary citationSarno, S.,Mazzorana, M.,Traynor, R.,Ruzzene, M.,Cozza, G.,Pagano, M.A.,Meggio, F.,Zagotto, G.,Battistutta, R.,Pinna, L.A.
Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A
Cell.Mol.Life Sci., 69:449-460, 2012
Cited by
PubMed: 21720886
DOI: 10.1007/s00018-011-0758-7
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

217157

건을2024-03-13부터공개중

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