3POB

Crystal structure of MASP-1 CUB2 domain in complex with the collagen-like domain of MBL

Summary for 3POB

Entry DOI	10.2210/pdb3pob/pdb
Descriptor	Mannan-binding lectin serine protease 1, MBL collagen-like peptide, CALCIUM ION, ... (4 entities in total)
Functional Keywords	collagen complex, masp, cub domain, mbl, mbp, collagen peptide, calcium binding site, complement proteins, lectin pathway of complement, masp-1, bloodstream, hydrolase
Biological source	Rattus norvegicus (brown rat,rat,rats) More
Cellular location	Secreted: Q8CHN8
Total number of polymer chains	4
Total formula weight	20570.69
Authors	Gingras, A.R.,Moody, P.C.E.,Wallis, R. (deposition date: 2010-11-22, release date: 2011-08-24, Last modification date: 2023-09-06)
Primary citation	Gingras, A.R.,Girija, U.V.,Keeble, A.H.,Panchal, R.,Mitchell, D.A.,Moody, P.C.,Wallis, R. Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation. Structure, 19:1635-1643, 2011 Cited by PubMed: 22078562 DOI: 10.1016/j.str.2011.08.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.801 Å)

Structure validation