3PO5

Structure of a mutant of the large fragment of DNA polymerase I from Thermus Auqaticus in complex with an abasic site and ddATP

Summary for 3PO5

• Entry DOI: 10.2210/pdb3po5/pdb
• Related: 3LWL 3LWM 3PO4
• Descriptor: DNA polymerase I, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3'), DNA (5'-D(P*(3DR)P*TP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (8 entities in total)
• Functional Keywords: dna polymerase, lesion bypass, apsite, abasic site, transferase-dna complex, transferase/dna
• Biological source: Thermus aquaticus
• Total number of polymer chains: 3
• Total formula weight: 69334.77

Authors

Marx, A.,Diederichs, K.,Obeid, S. (deposition date: 2010-11-22, release date: 2011-06-15, Last modification date: 2023-09-06)

• Primary citation: Obeid, S.,Schnur, A.,Gloeckner, C.,Blatter, N.,Welte, W.,Diederichs, K.,Marx, A.; Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity.; Chembiochem, 12:1574-1580, 2011; PubMed: 21480455; DOI: 10.1002/cbic.201000783

Experimental method

X-RAY DIFFRACTION (2.39 Å)