3PLF
Reverse Binding Mode of MetRD peptide complexed with c-Cbl TKB domain
Summary for 3PLF
Entry DOI | 10.2210/pdb3plf/pdb |
Descriptor | MetRD peptide, E3 ubiquitin-protein ligase CBL, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | c-cbl tkb domain, met, reverse binding, protein binding-ligase complex, protein binding/ligase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P22681 |
Total number of polymer chains | 4 |
Total formula weight | 79364.84 |
Authors | Sun, Q.,Sivaraman, J. (deposition date: 2010-11-15, release date: 2010-12-01, Last modification date: 2023-12-06) |
Primary citation | Sun, Q.,Ng, C.,Guy, G.R.,Sivaraman, J. An adjacent arginine, and the phosphorylated tyrosine in the c-Met receptor target sequence, dictates the orientation of c-Cbl binding Febs Lett., 585:281-285, 2011 Cited by PubMed: 21163258DOI: 10.1016/j.febslet.2010.11.060 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
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