3PIO

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit

3PIO の概要

• エントリーDOI: 10.2210/pdb3pio/pdb
• 関連するPDBエントリー: 1NKW 1SM1 1YI2 2ZJR 3JQ4 3PIP
• 分子名称: RIBOSOMAL 23S RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (34 entities in total)
• 機能のキーワード: ribosome, large ribosomal subunit, 50s, ribonucleoprotein, ribosomal protein, rna-binding, rrna-binding, trna-binding, lankamycin, lankacidin, macrolide, ribosome-antibiotic complex, ribosome/antibiotic
• 由来する生物種: Deinococcus radiodurans R1; 詳細
• タンパク質・核酸の鎖数: 30
• 化学式量合計: 1370433.47

構造登録者

Belousoff, M.J.,Shapira, T.,Bashan, A.,Zimmerman, E.,Arakawa, K.,Kinashi, H.,Rozenberg, H.,Yonath, A. (登録日: 2010-11-07, 公開日: 2011-02-23, 最終更新日: 2023-09-06)

• 主引用文献: Belousoff, M.J.,Shapira, T.,Bashan, A.,Zimmerman, E.,Rozenberg, H.,Arakawa, K.,Kinashi, H.,Yonath, A.; Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.; Proc.Natl.Acad.Sci.USA, 108:2717-2722, 2011; PubMed: 21282615; DOI: 10.1073/pnas.1019406108

実験手法

X-RAY DIFFRACTION (3.2473 Å)