Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3PIO

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0000049	molecular_function	tRNA binding
1	0003723	molecular_function	RNA binding
1	0003735	molecular_function	structural constituent of ribosome
1	0005737	cellular_component	cytoplasm
1	0005840	cellular_component	ribosome
1	0006412	biological_process	translation
1	0019843	molecular_function	rRNA binding
1	0022625	cellular_component	cytosolic large ribosomal subunit
1	1990904	cellular_component	ribonucleoprotein complex
2	0003723	molecular_function	RNA binding
2	0003735	molecular_function	structural constituent of ribosome
2	0005840	cellular_component	ribosome
2	0006412	biological_process	translation
2	0019843	molecular_function	rRNA binding
2	1990904	cellular_component	ribonucleoprotein complex
3	0003723	molecular_function	RNA binding
3	0003735	molecular_function	structural constituent of ribosome
3	0005840	cellular_component	ribosome
3	0006412	biological_process	translation
3	0019843	molecular_function	rRNA binding
3	0022625	cellular_component	cytosolic large ribosomal subunit
3	1990904	cellular_component	ribonucleoprotein complex
4	0003723	molecular_function	RNA binding
4	0003735	molecular_function	structural constituent of ribosome
4	0005737	cellular_component	cytoplasm
4	0005840	cellular_component	ribosome
4	0006412	biological_process	translation
4	0019843	molecular_function	rRNA binding
4	0046872	molecular_function	metal ion binding
4	1990904	cellular_component	ribonucleoprotein complex
A	0002181	biological_process	cytoplasmic translation
A	0003723	molecular_function	RNA binding
A	0003735	molecular_function	structural constituent of ribosome
A	0005840	cellular_component	ribosome
A	0006412	biological_process	translation
A	0015934	cellular_component	large ribosomal subunit
A	0016740	molecular_function	transferase activity
A	0019843	molecular_function	rRNA binding
A	1990904	cellular_component	ribonucleoprotein complex
B	0003723	molecular_function	RNA binding
B	0003735	molecular_function	structural constituent of ribosome
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0019843	molecular_function	rRNA binding
B	0022625	cellular_component	cytosolic large ribosomal subunit
B	1990904	cellular_component	ribonucleoprotein complex
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
C	0019843	molecular_function	rRNA binding
C	1990904	cellular_component	ribonucleoprotein complex
D	0000049	molecular_function	tRNA binding
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0019843	molecular_function	rRNA binding
D	0022625	cellular_component	cytosolic large ribosomal subunit
D	1990904	cellular_component	ribonucleoprotein complex
E	0002181	biological_process	cytoplasmic translation
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0019843	molecular_function	rRNA binding
E	0022625	cellular_component	cytosolic large ribosomal subunit
E	1990904	cellular_component	ribonucleoprotein complex
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0019843	molecular_function	rRNA binding
F	0022625	cellular_component	cytosolic large ribosomal subunit
F	0070180	molecular_function	large ribosomal subunit rRNA binding
F	1990904	cellular_component	ribonucleoprotein complex
G	0003723	molecular_function	RNA binding
G	0003729	molecular_function	mRNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0017148	biological_process	negative regulation of translation
G	0019843	molecular_function	rRNA binding
G	0022625	cellular_component	cytosolic large ribosomal subunit
G	1990904	cellular_component	ribonucleoprotein complex
H	0003723	molecular_function	RNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0015934	cellular_component	large ribosomal subunit
H	0019843	molecular_function	rRNA binding
H	0022625	cellular_component	cytosolic large ribosomal subunit
H	0070180	molecular_function	large ribosomal subunit rRNA binding
H	1990904	cellular_component	ribonucleoprotein complex
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0015934	cellular_component	large ribosomal subunit
I	0019843	molecular_function	rRNA binding
I	0022625	cellular_component	cytosolic large ribosomal subunit
I	1990904	cellular_component	ribonucleoprotein complex
J	0000049	molecular_function	tRNA binding
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0019843	molecular_function	rRNA binding
J	0022625	cellular_component	cytosolic large ribosomal subunit
J	1990904	cellular_component	ribonucleoprotein complex
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0019843	molecular_function	rRNA binding
K	0022625	cellular_component	cytosolic large ribosomal subunit
K	1990904	cellular_component	ribonucleoprotein complex
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005737	cellular_component	cytoplasm
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0008097	molecular_function	5S rRNA binding
L	0019843	molecular_function	rRNA binding
L	0022625	cellular_component	cytosolic large ribosomal subunit
L	1990904	cellular_component	ribonucleoprotein complex
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0019843	molecular_function	rRNA binding
M	0022625	cellular_component	cytosolic large ribosomal subunit
M	1990904	cellular_component	ribonucleoprotein complex
N	0000027	biological_process	ribosomal large subunit assembly
N	0003723	molecular_function	RNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0019843	molecular_function	rRNA binding
N	0022625	cellular_component	cytosolic large ribosomal subunit
N	1990904	cellular_component	ribonucleoprotein complex
O	0003723	molecular_function	RNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005737	cellular_component	cytoplasm
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0019843	molecular_function	rRNA binding
O	1990904	cellular_component	ribonucleoprotein complex
P	0003723	molecular_function	RNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0015934	cellular_component	large ribosomal subunit
P	0019843	molecular_function	rRNA binding
P	0022625	cellular_component	cytosolic large ribosomal subunit
P	1990904	cellular_component	ribonucleoprotein complex
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0019843	molecular_function	rRNA binding
Q	0022625	cellular_component	cytosolic large ribosomal subunit
Q	1990904	cellular_component	ribonucleoprotein complex
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0019843	molecular_function	rRNA binding
R	0022625	cellular_component	cytosolic large ribosomal subunit
R	1990904	cellular_component	ribonucleoprotein complex
S	0000049	molecular_function	tRNA binding
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0008097	molecular_function	5S rRNA binding
S	0019843	molecular_function	rRNA binding
S	0022625	cellular_component	cytosolic large ribosomal subunit
S	1990904	cellular_component	ribonucleoprotein complex
T	0000049	molecular_function	tRNA binding
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0019843	molecular_function	rRNA binding
T	0022625	cellular_component	cytosolic large ribosomal subunit
T	1990904	cellular_component	ribonucleoprotein complex
U	0003735	molecular_function	structural constituent of ribosome
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	1990904	cellular_component	ribonucleoprotein complex
V	0003723	molecular_function	RNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0019843	molecular_function	rRNA binding
V	0022625	cellular_component	cytosolic large ribosomal subunit
V	1990904	cellular_component	ribonucleoprotein complex
W	0003723	molecular_function	RNA binding
W	0003735	molecular_function	structural constituent of ribosome
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0015934	cellular_component	large ribosomal subunit
W	0019843	molecular_function	rRNA binding
W	0022625	cellular_component	cytosolic large ribosomal subunit
W	1990904	cellular_component	ribonucleoprotein complex
Z	0003723	molecular_function	RNA binding
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
Z	0008270	molecular_function	zinc ion binding
Z	0015934	cellular_component	large ribosomal subunit
Z	0019843	molecular_function	rRNA binding
Z	0046872	molecular_function	metal ion binding
Z	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	1
Number of Residues
Details

Chain

Residue

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE LMA X 2881

Chain	Residue
P	ARG111
X	C759
X	U760
X	A2041
X	A2045
X	G2484
X	C2589
X	U2590

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2883

Chain	Residue
X	U1286
X	G1284

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 2884

Chain	Residue
X	G2036
X	C2554
X	G2555
X	A2556

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 2886

Chain	Residue
X	U1280
X	A1281
X	C1989
X	A2031

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2887

Chain	Residue
X	A1282
X	A1988

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2888

Chain	Residue
X	A984

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 2889

Chain	Residue
X	C1310
X	C2689
X	A2690
X	A2692

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 2890

Chain	Residue
X	A2690
X	A2692
X	G2694

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2891

Chain	Residue
X	C1973

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2892

Chain	Residue
X	G2044
X	A2045

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2893

Chain	Residue
X	G2698

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 2894

Chain	Residue
X	A743
X	C744
X	A774
X	G776

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2895

Chain	Residue
X	C1340

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2896

Chain	Residue
X	G2039
X	A2040

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 2897

Chain	Residue
X	G579
X	G2426
X	A2427
X	C2478

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2898

Chain	Residue
X	C1979
X	A1980

site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2899

Chain	Residue
X	U1934

site_id	BC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2900

Chain	Residue
X	U2000

site_id	CC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2901

Chain	Residue
X	A2432

site_id	CC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2902

Chain	Residue
X	G1767

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2903

Chain	Residue
X	C1692
X	A1693

site_id	CC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2904

Chain	Residue
X	G2018

site_id	CC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 2905

Chain	Residue
X	G955
X	A956
X	G957

site_id	CC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2907

Chain	Residue
X	A2247
X	A2248

site_id	CC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2908

Chain	Residue
X	A512

site_id	CC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2909

Chain	Residue
X	A2497
X	A2520

site_id	CC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2910

Chain	Residue
X	G2621
X	G2622

site_id	DC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2912

Chain	Residue
O	SER76
X	G572

site_id	DC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2913

Chain	Residue
X	A2512

site_id	DC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2914

Chain	Residue
X	C226

site_id	DC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 2915

Chain	Residue
A	MET227
X	A796
X	A797
X	A2568

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 2916

Chain	Residue
X	C829
X	C830
X	U1199
X	G1201

site_id	DC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2917

Chain	Residue
X	U2572

site_id	DC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 206

Chain	Residue
C	ASN66
X	U1999

site_id	DC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2918

Chain	Residue
X	G1465
X	G2634

site_id	DC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2919

Chain	Residue
X	G1371
X	G1384

site_id	EC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2920

Chain	Residue
X	A576
X	U823

site_id	EC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2921

Chain	Residue
X	A762
X	C1283

site_id	EC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2922

Chain	Residue
X	A2043
X	G2481

site_id	EC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2923

Chain	Residue
X	G2426
X	G2481

site_id	EC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 2924

Chain	Residue
X	A1771
X	C1773
X	A1774

site_id	EC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2925

Chain	Residue
X	G751
X	G752

site_id	EC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2926

Chain	Residue
X	U753
X	G754

site_id	EC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 2927

Chain	Residue
X	U2563
X	G2560
X	G2561
X	G2562

site_id	EC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2928

Chain	Residue
X	C583
X	U585

site_id	FC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2929

Chain	Residue
X	A1681
X	A1682

site_id	FC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2930

Chain	Residue
X	G2665

site_id	FC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2931

Chain	Residue
X	C583

site_id	FC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2932

Chain	Residue
X	G798

site_id	FC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2933

Chain	Residue
X	U2057
X	G2218

site_id	FC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2935

Chain	Residue
X	G713

site_id	FC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2936

Chain	Residue
X	G1652
X	C1653

site_id	FC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2937

Chain	Residue
X	A1751
X	U1752

site_id	FC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2938

Chain	Residue
X	G2656

site_id	GC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2939

Chain	Residue
X	G2657

site_id	GC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2940

Chain	Residue
X	C1687
X	U1688

site_id	GC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2941

Chain	Residue
X	G687
X	A815

site_id	GC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 2943

Chain	Residue
X	A1681
X	A1682
X	G1684
X	G1975

site_id	GC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 2944

Chain	Residue
X	C2486
X	C2552
X	G2553
X	C2554

site_id	GC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG I 157

Chain	Residue
I	SER54
X	U839

site_id	GC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2947

Chain	Residue
X	G1273

site_id	GC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2949

Chain	Residue
X	U2594
X	C2595

site_id	GC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2950

Chain	Residue
X	A992

site_id	HC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG Y 124

Chain	Residue
X	A964
Y	G93

site_id	HC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2951

Chain	Residue
X	G2567

site_id	HC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2952

Chain	Residue
X	U954

site_id	HC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2953

Chain	Residue
X	G836
X	A2252

site_id	HC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2954

Chain	Residue
X	A2684

site_id	HC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 2955

Chain	Residue
X	A2409
X	U2410
X	A2411

site_id	HC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2956

Chain	Residue
X	A1953
X	A1954

site_id	HC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2957

Chain	Residue
X	G2661
X	A2701

site_id	HC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2958

Chain	Residue
X	C2431

site_id	IC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2959

Chain	Residue
X	U1280

site_id	IC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2960

Chain	Residue
X	G1333

site_id	IC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 2961

Chain	Residue
X	C169
X	A176
X	U2222

site_id	IC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 2962

Chain	Residue
X	U1034
X	G1035
X	G1036
X	U1037

site_id	IC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 2963

Chain	Residue
X	U2680
X	A2681
X	C2682

site_id	IC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2964

Chain	Residue
X	U2249

site_id	IC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2965

Chain	Residue
X	U800
X	C803

site_id	IC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2966

Chain	Residue
X	G165

site_id	IC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2967

Chain	Residue
X	C1411

site_id	JC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2968

Chain	Residue
X	U1690
X	U2531

site_id	JC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 2969

Chain	Residue
X	C541
X	G2018
X	C2019

site_id	JC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2970

Chain	Residue
X	A2025

site_id	JC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2972

Chain	Residue
X	U460
X	A483

site_id	JC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2973

Chain	Residue
X	U1656

site_id	JC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2974

Chain	Residue
X	C1311
X	U1656

site_id	JC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 2975

Chain	Residue
X	C1327
X	C1328
X	G1345

site_id	JC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2976

Chain	Residue
X	G462
X	C465

site_id	JC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2977

Chain	Residue
X	G1223
X	A1250

site_id	KC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2978

Chain	Residue
X	C1633

site_id	KC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2979

Chain	Residue
X	C1765

site_id	KC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2980

Chain	Residue
X	U1927
X	G1928

site_id	KC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2981

Chain	Residue
X	G831
X	G1201

site_id	KC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 2982

Chain	Residue
X	A595
X	U1262
X	G1263

site_id	KC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2983

Chain	Residue
X	A1278
X	U2594

site_id	KC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 2984

Chain	Residue
X	U839
X	U840
X	G2408
X	A2409

site_id	KC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2985

Chain	Residue
X	U1647
X	A1650

site_id	KC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2986

Chain	Residue
X	U170

site_id	LC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 2987

Chain	Residue
X	C1017
X	A1020
X	A1021

site_id	LC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2988

Chain	Residue
X	A1643

site_id	LC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 2989

Chain	Residue
X	A1001
X	C1002
X	G1200

site_id	LC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2990

Chain	Residue
X	C1663
X	G1664

site_id	LC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 2991

Chain	Residue
A	HIS234
A	THR241
X	G2576
X	A2577

site_id	LC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2992

Chain	Residue
X	G682
X	A683

site_id	LC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2993

Chain	Residue
X	A1289
X	C1663

site_id	LC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2994

Chain	Residue
X	A2432
X	U2471

site_id	LC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 2995

Chain	Residue
X	G844
X	A956

site_id	MC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 2996

Chain	Residue
X	A1408
X	A1619
X	C1620

site_id	MC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 2997

Chain	Residue
X	A70
X	A71
X	G111

site_id	MC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2998

Chain	Residue
X	G1266

site_id	MC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 2999

Chain	Residue
X	C1348

site_id	MC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 3000

Chain	Residue
X	G1407
X	A1408
X	C1620

site_id	MC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 3001

Chain	Residue
X	G875
X	A922

site_id	MC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 3002

Chain	Residue
X	G1284
X	A1285
X	G1664
X	C1665

site_id	MC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 3003

Chain	Residue
X	U974

site_id	MC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 3004

Chain	Residue
X	U1618
X	A1619

site_id	NC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 3005

Chain	Residue
X	G1360

site_id	NC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 3006

Chain	Residue
X	C1404
X	A1405

site_id	NC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 3007

Chain	Residue
X	U753
X	A1774
X	A1775

site_id	NC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 3008

Chain	Residue
X	C959
X	U973
X	U974

site_id	NC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 3009

Chain	Residue
Q	MET56
X	A1355
X	U1618

site_id	NC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 3010

Chain	Residue
X	G2052
X	G2053

site_id	NC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 3011

Chain	Residue
C	GLY79
X	G462
X	G464

site_id	NC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 3013

Chain	Residue
X	C2046
X	C2047
X	A2418

site_id	NC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 3014

Chain	Residue
N	ARG58
X	A1167

site_id	OC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 3015

Chain	Residue
X	G389
X	G406

site_id	OC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 3016

Chain	Residue
X	U585
X	A2482

site_id	OC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 3017

Chain	Residue
X	A1012

site_id	OC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 3018

Chain	Residue
X	G699
X	U784

site_id	OC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 3019

Chain	Residue
X	C31
X	C1214
X	C1252

site_id	OC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 3020

Chain	Residue
X	A797
X	G2567
X	A2568

site_id	OC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 3021

Chain	Residue
X	G2328
X	C2396
X	A2397

site_id	OC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 3022

Chain	Residue
X	C2431

site_id	OC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 3023

Chain	Residue
X	C1009
X	U1010
X	C1164

site_id	PC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 3024

Chain	Residue
X	A117
X	U118

site_id	PC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 3025

Chain	Residue
X	U839
X	C2406
X	G2407
X	G2408

site_id	PC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG X 3026

Chain	Residue
X	C2008

site_id	PC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 3027

Chain	Residue
I	PHE49
X	G229
X	U680

site_id	PC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 3028

Chain	Residue
X	G225
X	G399
X	U400

site_id	PC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 3029

Chain	Residue
X	A14
X	G15

site_id	PC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 3030

Chain	Residue
X	G395
X	G399

site_id	PC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG X 3031

Chain	Residue
X	A1391
X	U1392
X	G1393

site_id	PC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG X 3032

Chain	Residue
X	C78
X	G79

site_id	QC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA X 3035

Chain	Residue
X	A813
X	A815

site_id	QC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3036

Chain	Residue
X	U187

site_id	QC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA X 3038

Chain	Residue
X	G540
X	U2005

site_id	QC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA X 3039

Chain	Residue
X	A991
X	C993

site_id	QC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA Y 125

Chain	Residue
Y	G85

site_id	QC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA Z 61

Chain	Residue
X	C2591
Z	HIS4

site_id	QC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3040

Chain	Residue
X	G2393

site_id	QC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA X 3042

Chain	Residue
X	A1883
X	A1953

site_id	QC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3043

Chain	Residue
X	G1398

site_id	RC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3044

Chain	Residue
X	G57

site_id	RC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA X 3045

Chain	Residue
X	U29
X	G484

site_id	RC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3046

Chain	Residue
X	U2398

site_id	RC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3048

Chain	Residue
X	G1196

site_id	RC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3050

Chain	Residue
X	G2548

site_id	RC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA X 3051

Chain	Residue
X	G2527
X	G2528

site_id	RC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3052

Chain	Residue
X	G742

site_id	RC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA Y 126

Chain	Residue
Y	G99

site_id	RC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3055

Chain	Residue
X	U393

site_id	SC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA A 277

Chain	Residue
A	VAL248
A	THR249
X	A1796

site_id	SC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA X 3058

Chain	Residue
X	C982
X	G985

site_id	SC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3059

Chain	Residue
X	U1159

site_id	SC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA K 117

Chain	Residue
K	LEU10
K	ARG12
K	ASN13
K	ARG17

site_id	SC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3061

Chain	Residue
X	C2591

site_id	SC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3062

Chain	Residue
X	A1242

site_id	SC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3063

Chain	Residue
X	G531

site_id	SC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3064

Chain	Residue
X	C1358

site_id	SC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3065

Chain	Residue
X	G1450

site_id	TC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA X 3066

Chain	Residue
A	ARG240
X	U1819
X	G1820

site_id	TC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA X 3067

Chain	Residue
X	G171
X	A172
X	A174
X	C175

site_id	TC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA X 3068

Chain	Residue
X	G2647

site_id	TC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE K X 3070

Chain	Residue
X	G2015

site_id	TC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE K X 3072

Chain	Residue
X	G608

site_id	TC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE K X 3074

Chain	Residue
X	U1467
X	A1468

site_id	TC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE K X 3076

Chain	Residue
X	A2618
X	G2619

site_id	TC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE K X 3077

Chain	Residue
X	C574
X	U823
X	G1266

site_id	TC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE K X 3078

Chain	Residue
X	G1316
X	G1317
X	C1623

site_id	UC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE K X 3081

Chain	Residue
X	G844
X	A956

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtshaikra.DGstirFdrNaaVI

Chain	Residue	Details
H	ALA72-ILE98

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAIVRLAegqsieaL

Chain	Residue	Details
Q	LYS76-LEU91

site_id	PS00359
Number of Residues	16
Details	RIBOSOMAL_L11 Ribosomal protein L11 signature. NtVaGTarSMGvTVeG

Chain	Residue	Details
F	ASN125-GLY140

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. KrlIpRArGSaniikkrtSHITIiV

Chain	Residue	Details
P	LYS104-VAL128

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PhqRGSAmNPvD

Chain	Residue	Details
A	PRO220-ASP231

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FaegekiDatGtSkGKGtqGvmkR

Chain	Residue	Details
B	PHE96-ARG119

site_id	PS00475
Number of Residues	31
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KLLAsGeIsra..VtVhvdaASaaAikaVeaaG

Chain	Residue	Details
I	LYS107-GLY137

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. QPHRVRqLRREVAQL

Chain	Residue	Details
V	GLN39-LEU53

site_id	PS00582
Number of Residues	20
Details	RIBOSOMAL_L33 Ribosomal protein L33 signature. YtTtKNrrntQakLElkKYD

Chain	Residue	Details
1	TYR22-ASP41

site_id	PS00586
Number of Residues	12
Details	RIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. RRgGKIYIRIFP

Chain	Residue	Details
J	ARG60-PRO71

site_id	PS00701
Number of Residues	12
Details	RIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGkGKGaveyW

Chain	Residue	Details
J	ARG83-TRP94

site_id	PS00783
Number of Residues	23
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VFGMLPkgrq.GRamhtrLkVYaG

Chain	Residue	Details
G	VAL131-GLY153

site_id	PS00784
Number of Residues	20
Details	RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTYQpnnrkRakth.GFraR

Chain	Residue	Details
2	LYS2-ARG21

site_id	PS00828
Number of Residues	26
Details	RIBOSOMAL_L36 Ribosomal protein L36 signature. CdnCkvVrRhgrVlViCsnv.KHkQrQ

Chain	Residue	Details
4	CYS11-GLN36

site_id	PS00831
Number of Residues	15
Details	RIBOSOMAL_L27 Ribosomal protein L27 signature. GnILvRQRGtkfkaG

Chain	Residue	Details
T	GLY34-GLY48

site_id	PS00936
Number of Residues	27
Details	RIBOSOMAL_L35 Ribosomal protein L35 signature. KTHkMAkRRIkitgtgkvmafksgk.RH

Chain	Residue	Details
3	LYS5-HIS31

site_id	PS00937
Number of Residues	17
Details	RIBOSOMAL_L20 Ribosomal protein L20 signature. KrdfRrLWIQRINagaR

Chain	Residue	Details
N	LYS54-ARG70

site_id	PS01015
Number of Residues	16
Details	RIBOSOMAL_L19 Ribosomal protein L19 signature. IvErGKVR.RAKLYYLR

Chain	Residue	Details
M	ILE93-ARG108

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. GDtViVLsGkhKGqt.GkV

Chain	Residue	Details
R	GLY19-VAL36

site_id	PS01167
Number of Residues	23
Details	RIBOSOMAL_L17 Ribosomal protein L17 signature. IqTTltKaKelrpfvEqLITtAK

Chain	Residue	Details
K	ILE34-LYS56

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	23
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	103
Details	Region: {"description":"N-terminal domain"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	16
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P80256","evidenceCode":"ECO:0000250"},{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)