3PGF

Crystal structure of maltose bound MBP with a conformationally specific synthetic antigen binder (sAB)

3PGF の概要

• エントリーDOI: 10.2210/pdb3pgf/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900001
• 分子名称: Maltose-binding periplasmic protein, SAB Heavy Chain, SAB Light Chain, ... (7 entities in total)
• 機能のキーワード: maltodextrin binding protein, fab, antibody fragment, engineered binding protein, maltodextrin binding protein-de novo protein complex, maltodextrin binding protein/de novo protein
• 由来する生物種: Escherichia coli; 詳細
• 細胞内の位置: Periplasm: P0AEX9; Secreted : P0DOX5
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 92840.60

構造登録者

Kossiakoff, A.A.,Duguid, E.M.,Sandstrom, A. (登録日: 2010-11-01, 公開日: 2011-03-09, 最終更新日: 2023-09-06)

• 主引用文献: Rizk, S.S.,Paduch, M.,Heithaus, J.H.,Duguid, E.M.,Sandstrom, A.,Kossiakoff, A.A.; Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins.; Nat.Struct.Mol.Biol., 18:437-442, 2011; PubMed: 21378967; DOI: 10.1038/nsmb.2002

実験手法

X-RAY DIFFRACTION (2.1 Å)