3PFH

X-Ray crystal structure the N,N-dimethyltransferase TylM1 from Streptomyces fradiae in complex with SAH and dTDP-Quip3N

3PFH の概要

• エントリーDOI: 10.2210/pdb3pfh/pdb
• 関連するPDBエントリー: 3PFG
• 分子名称: N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, [(3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl][hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate, ... (5 entities in total)
• 機能のキーワード: n, n-dimethyltransferase, sam binding, dtdp-linked sugar binding, transferase
• 由来する生物種: Streptomyces fradiae
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 59001.35

構造登録者

Carney, A.E.,Holden, H.M. (登録日: 2010-10-28, 公開日: 2010-12-15, 最終更新日: 2023-09-06)

• 主引用文献: Carney, A.E.,Holden, H.M.; Molecular Architecture of TylM1 from Streptomyces fradiae: An N,N-Dimethyltransferase Involved in the Production of dTDP-d-mycaminose .; Biochemistry, 50:780-787, 2011; PubMed: 21142177; DOI: 10.1021/bi101733y

実験手法

X-RAY DIFFRACTION (1.792 Å)