3PBA
Crystal structure of PPARgamma ligand binding domain in complex with monosulfate tetrabromo-bisphenol A (MonoTBBPA)
Summary for 3PBA
Entry DOI | 10.2210/pdb3pba/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, 2,6-dibromo-4-[2-(3,5-dibromo-4-hydroxyphenyl)propan-2-yl]phenyl hydrogen sulfate, S-1,2-PROPANEDIOL, ... (4 entities in total) |
Functional Keywords | transcription, ligand binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P37231 |
Total number of polymer chains | 2 |
Total formula weight | 65945.52 |
Authors | le Maire, A.,Bourguet, W. (deposition date: 2010-10-20, release date: 2011-06-08, Last modification date: 2024-02-21) |
Primary citation | Riu, A.,le Maire, A.,Grimaldi, M.,Audebert, M.,Hillenweck, A.,Bourguet, W.,Balaguer, P.,Zalko, D. Characterization of Novel Ligands of ER{alpha}, Er{beta}, and PPAR{gamma}: The Case of Halogenated Bisphenol A and Their Conjugated Metabolites. Toxicol Sci, 122:372-382, 2011 Cited by PubMed: 21622942DOI: 10.1093/toxsci/kfr132 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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