3P87

Structure of human PCNA bound to RNASEH2B PIP box peptide

Summary for 3P87

Related3P83 1AXC
DescriptorProliferating cell nuclear antigen, Ribonuclease H2 subunit B (2 entities in total)
Functional Keywordsdna binding, dna replication, dna repair, sliding clamp, pcna peptide interacting peptide (pip) motif, pip-box motif, dna clamp, processivity factor, rnase h2, fen-1, ligase, polymerases, helicases, nucleases, nucleus, hydrolase-dna binding protein complex, hydrolase/dna binding protein
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus P12004
Nucleus (Probable) Q5TBB1
Total number of polymer chains12
Total molecular weight188153.04
Authors
Bubeck, D.,Reijns, M.A.,Graham, S.C.,Astell, K.R.,Jones, E.Y.,Jackson, A.P. (deposition date: 2010-10-13, release date: 2011-02-02, Last modification date: 2014-04-02)
Primary citation
Bubeck, D.,Reijns, M.A.,Graham, S.C.,Astell, K.R.,Jones, E.Y.,Jackson, A.P.
PCNA directs type 2 RNase H activity on DNA replication and repair substrates.
Nucleic Acids Res., 39:3652-3666, 2011
PubMed: 21245041 (PDB entries with the same primary citation)
DOI: 10.1093/nar/gkq980
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.99 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.26660.8%4.5%4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution