3P5P

Crystal Structure of Taxadiene Synthase from Pacific Yew (Taxus brevifolia) in complex with Mg2+ and 13-aza-13,14-dihydrocopalyl diphosphate

Summary for 3P5P

Entry DOI	10.2210/pdb3p5p/pdb
Related	3P5R
Descriptor	Taxadiene synthase, MAGNESIUM ION, 2-(methyl{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidenedecahydronaphthalen-1-yl]ethyl}amino)ethyl trihydrogen diphosphate, ... (5 entities in total)
Functional Keywords	class i and ii terpene cyclase fold, diterpene cyclase, ddxxd motif, nse/dte motif, 3-azacopalyl diphosphate, biosynthesis of paclitaxel, lyase
Biological source	Taxus brevifolia (Pacific yew)
Total number of polymer chains	1
Total formula weight	88967.64
Authors	Koksal, M.,Christianson, D.W. (deposition date: 2010-10-10, release date: 2010-12-29, Last modification date: 2024-02-21)
Primary citation	Koksal, M.,Jin, Y.,Coates, R.M.,Croteau, R.,Christianson, D.W. Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis. Nature, 469:116-120, 2011 Cited by PubMed: 21160477 DOI: 10.1038/nature09628 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.816 Å)

Structure validation