3P46

Integrin binding collagen peptide

Summary for 3P46

• Entry DOI: 10.2210/pdb3p46/pdb
• Descriptor: Synthetic collagen peptide (2 entities in total)
• Functional Keywords: collagen, integrin recognition, integrin alpha 1 beta 1, de novo protein
• Biological source: artificial gene
• Total number of polymer chains: 3
• Total formula weight: 4955.26

Authors

McEwan, P.A.,Emsley, J. (deposition date: 2010-10-06, release date: 2011-01-12, Last modification date: 2025-03-26)

Primary citation

Byrne, C.,McEwan, P.A.,Emsley, J.,Fischer, P.M.,Chan, W.C.
End-stapled homo and hetero collagen triple helices: a click chemistry approach.
Chem.Commun.(Camb.), 47:2589-2591, 2011

PubMed Abstract: A CuAAC reaction was established for modular synthesis of end-stapled homo- and hetero-triple helical peptides, generating "clicked" macro-assemblies with enhanced thermal stability.

PubMed: 21173963
DOI: 10.1039/c0cc04795c

Experimental method

X-RAY DIFFRACTION (1.7 Å)