3OXF
Human lysine methyltransferase Smyd3 in complex with AdoHcy (Form I)
Summary for 3OXF
Entry DOI | 10.2210/pdb3oxf/pdb |
Related | 3OXG |
Descriptor | SET and MYND domain-containing protein 3, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... (4 entities in total) |
Functional Keywords | smyd proteins, mynd, set domain, histone lysine methyltransferase, histone methylation, h3k4, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : Q9H7B4 |
Total number of polymer chains | 2 |
Total formula weight | 101659.80 |
Authors | |
Primary citation | Xu, S.,Wu, J.,Sun, B.,Zhong, C.,Ding, J. Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding. Nucleic Acids Res., 39:4438-4449, 2011 Cited by PubMed: 21266482DOI: 10.1093/nar/gkr019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.82 Å) |
Structure validation
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