3OXF

Human lysine methyltransferase Smyd3 in complex with AdoHcy (Form I)

3OXF の概要

• エントリーDOI: 10.2210/pdb3oxf/pdb
• 関連するPDBエントリー: 3OXG
• 分子名称: SET and MYND domain-containing protein 3, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... (4 entities in total)
• 機能のキーワード: smyd proteins, mynd, set domain, histone lysine methyltransferase, histone methylation, h3k4, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm : Q9H7B4
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 101659.80

構造登録者

Xu, S.,Wu, J.,Sun, B.,Zhong, C.,Ding, J. (登録日: 2010-09-21, 公開日: 2011-02-23, 最終更新日: 2023-11-01)

• 主引用文献: Xu, S.,Wu, J.,Sun, B.,Zhong, C.,Ding, J.; Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding.; Nucleic Acids Res., 39:4438-4449, 2011; PubMed: 21266482; DOI: 10.1093/nar/gkr019

実験手法

X-RAY DIFFRACTION (2.82 Å)