3OP0

Crystal structure of Cbl-c (Cbl-3) TKB domain in complex with EGFR pY1069 peptide

3OP0 の概要

• エントリーDOI: 10.2210/pdb3op0/pdb
• 分子名称: Signal transduction protein CBL-C, Epidermal growth factor receptor, SODIUM ION, ... (5 entities in total)
• 機能のキーワード: structural genomics, structural genomics consortium, sgc, signal transduction protein, sh3-binding protein, signaling protein-signaling protein regulator complex, signaling protein/signaling protein regulator
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: P00533
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 75084.49

構造登録者

Chaikuad, A.,Guo, K.,Cooper, C.D.O.,Ayinampudi, V.,Krojer, T.,Ugochukwu, E.,Muniz, J.R.C.,Vollmar, M.,Canning, P.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Bountra, C.,Bullock, A.,Structural Genomics Consortium (SGC) (登録日: 2010-08-31, 公開日: 2010-10-20, 最終更新日: 2023-12-06)

• 主引用文献: Chaikuad, A.,Guo, K.,Cooper, C.D.O.,Ayinampudi, V.,Krojer, T.,Ugochukwu, E.,Muniz, J.R.C.,Vollmar, M.,Canning, P.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Bountra, C.,Bullock, A.; Crystal structure of Cbl-c (Cbl-3) TKB domain in complex with EGFR pY1069 peptide; To be Published,

実験手法

X-RAY DIFFRACTION (2.52 Å)